Natural Betaine Powder

For use in:
✓ Food Beverages
✓ Dietary Supplements
✓ Cosmetics

Health Benefits

✓ "Methyl" Donor
✓ Homocysteine Metabolization
✓ Cellular Osmolyte

Athletic Performance

✓ Increased Strength, Power Endurance
✓ Superior Cellular Hydration Protection

Homocysteine Reduction

✓ Activates Homocysteine Metabolization
✓ Effective for Moderately Severely-Elevated Levels

Prenatal Nutrition

✓ Vital Nutrient in Prenatal Diets
✓ Fosters Healthy Brain Development

Other Benefits


✓ Clinically-Validated
✓ Human Safety Efficacy Studies


Betaine PURE is a 100% all-natural ingredient from the molasses of sugar beets. Farmer-grown in the USA, Betaine PURE is available in a >99% pure betaine powder grade.

Betaine is a naturally occurring trimethylated molecule of the amino acid glycine found in many healthy foods such as whole grains, spinach, broccoli, shellfish and beets. A long-time beneficial staple of Mediterranean diets, betaine has recently been the subject of numerous studies demonstrating benefits to overall health and performance.

Betaine is also known as:

  • Trimethylglycine (TMG)
  • Betaine Anhydrous
  • Glycine Betaine

Clinically-validated human trials have demonstrated that natural betaine can lead to improved athletic performance. The FDA has approved a health claim for the ability of natural betaine to reduce high levels of homocysteine and medical condition known as homocystinuria.

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Research has demonstrated additional health benefits for skin care, immune health, brain health, prenatal nutrition, and kidney and liver health.

IMPORTANT NOTE: Synthetic betaine (known as trimethyl amine hydrochloride, TMA, or Betaine HCl) is often marketed as a substitute to the all-natural version and the labeling of these synthetic products is often misleading. These products have not been subject to the same stringent safety and efficacy studies as the natural ingredient such Betaine PURE.

Product Description

Common Name: Betaine
Other Names: Trimethylglycine; Betaine Anhydrous; Glycine betaine

Origin: Sugar Beets (Beta Vulgaris)
CAS Number: 107-43-7
Pubchem Substance ID: 24882186
EG/EC Number: 203-490-6



Pack Size: 20 kg
Bag Style: pinch bottom, glued top
Bag Colors White: with Betaine Pure logo and manufacturing label
Bag Construction: 3-ply kraft outer with 1 ply (1200 micron) poly liner, independently sealed

Batch Indentification  
Lot number by production day; pallet identification by time stamp.
Product PropertiesCosmetic/Food GradePharmaceutical Grade
Molecular Weight:117.146117.146
Molecular Formula:C5H11NO2C5H11NO2
Bulk Volume:0.6 - 0.8 kg/l0.6 - 0.8 kg/l
Betaine Solubility at 25 C  
Water:160 g/100g160 g/100g
Methanol:55 g/100g55 g/100
Ethanol:8.7 g/100g8.7 g/100g
Product CharacteristicsCosmetic/Food GradePharmaceutical Grade
Appearance:Free flowing PowderFree flowing Powder
Color:White (ICUMSA <20)White (ICUMSA <20)
Product SpecificationsCosmetic/Food GradePharmaceutical Grade
Betaine (HPLC)>96% DS>99% DS
Chloride<50 ppm<50 ppm
Sulphate<100 ppm<100 ppm
Heavy Metals<10 ppm<10 ppm
Arsenic<1 ppm<1 ppm
pH5 -75 -7
Microbiological SpecificationsCosmetic/Food GradePharmaceutical Grade
Total Plate Count<100 cfu/g<100 cfu/g
Yeast<10 cfu/g<10 cfu/g
Mold<10 cfu/g<10 cfu/g
ColiformsNot DetectedNot Detected
SalmonellaNot DetectedNot Detected
E.coliNot DetectedNot Detected

Quality Assurance
Strict quality control procedures are enforced during manufacture. The manufacturing environment is subject to strict monitoring and control in accordance with HACCP/GMP requirements.

Final product is sampled and tested for chemical, and physical parameters using internationally recognized procedures.

Storage Handling
This product is hygroscopic and must be stored in unopened bags and in a humidity controlled environment.

All products delivered from Snake River Nutrition are packaged in multi walled paper bags, which are packed on pallets with a pallet cover on the pallet. The pallets are then wrapped with stretch film with a both a plastic and a cardboard top cover. Deliveries are made at ambient temperature using a standard enclosed van.

Safety Handling
Provide good ventilation and avoid dust formation. It is recommended to use protective glasses, respiratory mask and glover during handling. Incase of accidental contact with skin or eye, the only action needed is flushing with water. See the MSDS for further information.

Kosher Status

Allergen Information

Country of Origin
Grown, produced and packaged in United States of America.

Material Safety Data Sheet

Online MSDS Coming Soon.

Betaine (trimethylglycine) functions very closely with choline, folic acid, vitamin B12, and a form of the amino acid methionine known as S-adenosylmethionine (SAMe).

Like these other compounds, betaine functions as a “methyl donor.” Betaine carries and donates methyl molecules to facilitate necessary chemical processes. The donation of methyl groups by betaine is very important to proper liver function, cellular replication, and detoxification reactions.

Betaine is closely related to choline. The difference is that choline (tetramethylglycine) has four methyl groups attached to it. When choline donates one of these groups to another molecule, it becomes betaine (trimethylglycine).

Betaine also plays a role in the manufacture of carnitine and serves to protect the kidneys from damage.

Natural betaine supplementation has been shown in studies to have positive effect on athletic performance. In particular, betaine supplementation can improve the strength, power, and endurance of athletes.

Betaine acts on a cellular level as an organic osmolyte that supports cell metabolism. Through this activity, betaine supports the protection of cells against dehydration and stress-related water loss. When supplemented in a beverage in conjunction with electrolytes, this combination will synergistically provide superior hydration to athletes.

All-natural Betaine PURE is readily bio-available and improve performance through:

  • Enhanced Endurance
  • Better Oxygen Utilization
  • Reduced Lactic Acid Buildup
  • Faster Muscle Recovery

Potential applications include:

  • Gels
  • Sports Energy Bars
  • Drink Mixes Ready-to-Drink Beverages
Homocysteine is an amino acid that inflicts damage to the inner arterial lining (endothelium) and other cells of the body.

All homocysteine in the body is biosynthesized from methionine, an essential amino acid found abundantly in meats, seafood, dairy products, and eggs. Betaine donates a methyl group in the biosynthesis of homocysteine back to the methionine.

Ideally, homocysteine is metabolized by the body as part of the process for creating essential hormones such as glutathione, serotonin, melatonin, dopamine, and adrenaline. Elevated homocysteine levels are the result, however, of a lack of necessary vitamins, minerals and nutrients needed to metabolize homocysteine.

Additionally, in certain rare genetic conditions, the body cannot dispose of homocysteine, resulting in its accumulation to extremely high levels (homocystinuria).

Betaine greatly reduces homocysteine levels and improves health among people with homocystinuria as well as individuals with relatively mild homocysteine elevations.

Like folate (folic acid) and choline, betaine is an essential prenatal nutrient that expecting mothers should add to their diets In fact, researchers suspect that the three may work synergistically together. The American Journal of Epidemiology reported that babies born to women whose diets were highest in choline and betaine were 75 percent less likely to have neural tube defects than babies born to women with the lowest levels of these nutrients.

In addition, betaine has been receiving increasing recognition as a nutrient necessary for the proper formation of the developing brain’s memory center.

It is important that prenatal nutrition products are formulated only using all-natural betaine sources such as Betaine PURE. The synthetic version of betaine (betaine HCl) has not been verified as effective in any research studies, and the synthetic version also carries with many side effects including nausea, diarrhea and vomiting and cannot be used by individuals suffers from acid reflux or stomach ulcers.



Betaine PURE is being distributed through a collaboration between TMG Diversified (St. Paul, MN ) and Catalyst3 (Minneapolis, MN).

We employ a customer-focused attitude and a long-term commitment to our clients. We have been involved in betaine development with our farmers for over 16 years and guarantee that we only source 100% natural betaine which is grown, processed and packaged in the USA.

Corporate Address:
889 Pierce Butler Route
Saint Paul, Minnesota USA

Any statements on this site have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have any medical condition, we suggest consulting with a physician before using any of our products. Individual results may vary.
© 2014 Catalyst3 LLC, Minneapolis, Minnesota 55376. All Rights Reserved.